The first generation Honda S2000 made its debut as a roadster in 2000. The vehicle was launched with one version only that was powered by a 240 horsepower 2.0Liter engine. The vehicle seats 2, but there is no space in it to store luggage. The instrument panel in front of the driver is dominated by one instrument, a tachometer, with the other gauges that show fuel left in the car and coolant, less conspicuous. The back window is made of plastic as Honda wanted to keep the weight of the vehicle low. The S2000 comes equipped with seats made of leather, air conditioning, a music system that can play AM/FM and CDs. All the windows and mirrors can be operated by the touch of a button and one can enter the roadster with the help of a remote. In 2002, the rear window got glass windows, new rear lights, and a better music system. In the year 2004, the roadster got 17 inch tires, better shock absorbers, and a new 2.2 Liter engine was added to its line up. The company continued to make changes to the Honda S2000 in 2006 and 2007, when it added more speakers to the cars music system, and more padding for the headrests.

In the model year 2008, a new version was added to the Line up of the S2000 which it called the club racer model. The new version got a stronger suspension and new tires manufactured by Bridgestone. To keep the weight low of the new S200 low, the spare wheel has been removed. No changes have been made to the engines which remain the same. The base version of the Honda S2000 is equipped with a roof that can be opened or closed with the touch of a button, a rear window made of glass and which can defrost ice that gets accumulated on it, seats made of leather, headlights made of Xenon, 17 inch tires and a CD based music system.